@article{Baedowi_Zulfian_Rusmini_Prasetia_2020, title={Hubungan Jumlah Viral Load dengan Kejadian TBC pada Pasien HIV/AIDS yang Mendapatkan Terapi ARV }, volume={1}, url={https://arteri.sinergis.org/arteri/article/view/76}, DOI={10.37148/arteri.v1i3.76}, abstractNote={<p style="text-align: justify;"><em>Viral Load (VL) is a direct indicator of the total amount of cells produced by the virus in a person infected with HIV. TB becomes a challenge for controlling Acquired Immunodeficiency Syndrome (AIDS) because it is the most opportunistic infection in people living with HIV / AIDS (PLWHA). TB can increase HIV progression and the risk of death for people living with HIV.</em> <em>Immunosuppression can increase the likelihood that dormant TB germs reactivate. The pathogenesis of TB infection in HIV patients is directly related to the decline in the immune system, specifically CD4 T lymphocytes. HIV infection will cause a decrease in CD4 T lymphocytes thereby reducing the immunological response to Mycobacterium tuberculosis. This will result in reactivation from the latent period of TB to an active infection. </em><em>This study conducted to discover the relationship between the amount of viral load and the tuberculosis case in HIV / AIDS patients that undertake ARV therapy at RSUD Dr. H. Abdul Moeloek Lampung Province in 2019.&nbsp;</em><em>Observational analytic approach with cross sectional design was used in this present study.&nbsp; </em><em>The data taken is secondary data from the medical record of HIV / AIDS patients in Dr. H. Abdul Moeloek Lampung Province in 2019.</em> <em>The sampling technique used was a purposive sampling method and it was obtained a total sample of 196 people. The data was analyzed through Chi Square test. There was a significant relationship between the amount of viral load in HIV / AIDS patients and the tuberculosis case (p-value = 0.004). From the analysis above, it was obtained OR value = 2.52 which represents that patients who have a viral load ≥ 10,000 have a risk of 2.52 times to encounter TB. A high amount of Viral Load can cause immunosuppression in the host and increase the virulence of TB microbes.</em></p&gt;}, number={3}, journal={ARTERI : Jurnal Ilmu Kesehatan}, author={Baedowi, Andri and Zulfian and Rusmini, Hetti and Prasetia, Toni}, year={2020}, month={May}, pages={233-240} }